Altered speech patterns in subjects with post-traumatic headache due to mild traumatic brain injury

Abstract Background/objective Changes in speech can be detected objectively before and during migraine attacks. The goal of this study was to interrogate whether changes subjects with post-traumatic headache (PTH) attributed mild traumatic brain injury (mTBI) there are within-subject headaches compared the headache-free state. Methods Using a series elicitation tasks uploaded via mobile application, PTH healthy controls (HC) provided samples once every 3 days, over period 12 weeks. following parameters were assessed: vowel space area, articulation precision, consonant average pitch, pitch variance, speaking rate pause rate. Speech HC. To assess associated PTH, when headache-free. All analyses conducted using mixed-effect model design. Results Longitudinal collected from nineteen (mean age = 42.5, SD 13.7) who an 14 days (SD 32.2) their mTBI at time enrollment thirty-one HC 38.7, 12.5). Regardless presence or absence, had longer rates reductions precision relative On headache, rates, slower sentence less precise production During yet more they Conclusions Compared HC, acute demonstrate altered as measured by objective features production. For individuals may have been effortful resulting vs. headache-free, suggesting that alterations related not solely due underlying mTBI.